Accession Therapeutics presents first-in-human ATTEST trial at the European Society for Medical Oncology (ESMO) Congress 2025
- Oct 17, 2025
- 1 min read
Updated: Oct 27, 2025
At the ESMO Congress 2025, taking place between 17-21 October, Accession Therapeutics are sharing details of our ATTEST study, a first-in-human Phase 1 trial of ATTR-01 (TROCEPT-01) in patients with selected epithelial tumours.
ATTR-01 is a next-generation oncolytic adenovirus developed using Accession's proprietary TROCEPT platform. It is designed to target the cancer marker αvβ6 integrin and express an anti-PD-L1 antibody payload locally within the tumour micro-environment following intravenous delivery.
The ATTEST study (NCT06977737) is now open and will involve patients with non-small cell lung cancer, bladder, pancreatic, head and neck, cholangiocarcinoma and endometrial cancers across multiple leading sites in the UK and Spain.
Hardev Pandha, Medical Director at Accession Therapeutics, said:
“ATTR-01 represents a new way to deliver checkpoint inhibition where it’s needed most - within tumours - while minimising systemic exposure.”
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